Nayf nutters
- BTW for the amusement of Nayf, an Alitalia representative once told me to 'go **** myself' before she put the phone down.
- Pmc.ncbi.nlm.nih.gov › articles › PMC10598172.
- This article presents state-of-the-art optical probes derived from neurotoxins targeting ion channels, with discussions of their applications in basic and.
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Grecale New & Images
I think the point of the Grecale is the same as the point of the Ghibli. For me the Ghibli represented an attainable point to be able to own a new Maserati. Six years ago when I ordered my car, after options but before a healthy discount it was circa £70k. For the same money you were looking at E class 5 series, or in my case another Jaguar in the shape of the then second generation new XF. The simple fact why buy one of the usual executive saloon choices, all very capable but all too familiar and boring, when you can get a new Maserati which when fully specked does the luxury and exclusivity thing so much better, and the fact that it's got a diesel engine was not nor has never been since an issue!
The same will be the case with the Grecale, why have a common as muck BMW etc SUV when you can say you own a Maserati.
From my own prospective, I would like to stay with the brand but I will have to see whether the new electric 4 door that is rumoured will be affordable, or if as it's repIlacing both current saloons, if it's going to pitched beyond me into th
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Abstract
The superb specificity and potency of biological toxins targeting various ion channels and receptors are of major interest for the delivery of therapeutics to distinct cell types and subcellular compartments. Fused with reporter proteins or labelled with fluorophores and nanocomposites, animal toxins and their detoxified variants also offer expanding opportunities for visualisation of a range of molecular processes and functions in preclinical models, as well as clinical studies. This article presents state-of-the-art optical probes derived from neurotoxins targeting ion channels, with discussions of their applications in basic and translational biomedical research. It describes the design and production of probes and reviews their applications with advantages and limitations, with prospects for future improvements. Given the advances in imaging tools and expanding research areas benefiting from the use of optical probes, described here resources should assist the discovery process and facilitate high-precision interrogation and therapeutic interventions.
Keywords: An
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Au nanoparticle@silica@europium coordination polymer nanocomposites for enhanced fluorescence and more sensitive monitoring reactive oxygen species
Abstract
Au nanoparticle (Au NP)@SiO2@TDA-Eu nanocomposites were prepared by a two-step process: Au NP@SiO2 nanocomposites were prepared by a modified onepot process. Then the europium coordination polymer was deposited on the surface of the Au NP@SiO2 by mixing 2,2’-thiodiacetic acid [S(CH2COO)22-, TDA] and Eu(NO3)3·6H2O in ethanol via a hydrothermal method. The maximum fluorescent enhancement factor of the nanocomposites was 6.81 at 30 nm thickness of silica between the core of the Au NP and the shell of TDA-Eu. The prepared nanocomposites exhibit more sensitive monitoring of reactive oxygen species.
摘要
本论文通过两步工艺成功合成了Au NP@SiO2@TDA-Eu复合纳米材料:采用改进的一锅法制备了纳米复合材料Au NP@SiO2,然后 利用水热法, 在无水乙醇中通过亚硫基二乙酸[S(CH2COO)22-, TDA]和EUNO3)3·6H2O反应, 生成铕的配位聚合物, 并将其沉积在Au NP@SiO2的表面合成复合纳米材料Au NP@SiO2@TDA-Eu.该复合材料在二氧化硅层厚度为30 nm时, 荧光增强最大, 增强因子为6.81,在 对活性氧的检测中,表现出高灵敏度.
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